Entresto protected the cardiomyocytes and preserved heart function in cardiorenal syndrome rat fed with high-protein diet through regulating the oxidative stress and Mfn2-mediated mitochondrial functional integrity

This study tested the hypothesis that Entresto (En) therapy protected the cardiomyocytes and heart function in cardiorenal syndrome (CRS) rats fed with high-protein diet (HPD) through regulating the oxidative-stress and Mfn2-mediated mitochondrial functional integrity. En (12.5 μM for the in-vitro s...

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Autores principales: Jui-Ning Yeh, Ya Yue, Yi-Ching Chu, Chi-Ruei Huang, Chih-Chao Yang, John Y. Chiang, Hon-Kan Yip, Jun Guo
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/36b31e3bfbd24590aa7e28d37939ce6e
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