Cortical actin nanodynamics determines nitric oxide release in vascular endothelium.

The release of the main vasodilator nitric oxide (NO) by the endothelial NO synthase (eNOS) is a hallmark of endothelial function. We aim at elucidating the underlying mechanism how eNOS activity depends on cortical stiffness (К(cortex)) of living endothelial cells. It is hypothesized that cortical...

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Autores principales: Johannes Fels, Pia Jeggle, Kristina Kusche-Vihrog, Hans Oberleithner
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/36fc7a35d50943c4bcbf5e66c5ce99bb
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