Cortical actin nanodynamics determines nitric oxide release in vascular endothelium.
The release of the main vasodilator nitric oxide (NO) by the endothelial NO synthase (eNOS) is a hallmark of endothelial function. We aim at elucidating the underlying mechanism how eNOS activity depends on cortical stiffness (К(cortex)) of living endothelial cells. It is hypothesized that cortical...
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Main Authors: | Johannes Fels, Pia Jeggle, Kristina Kusche-Vihrog, Hans Oberleithner |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/36fc7a35d50943c4bcbf5e66c5ce99bb |
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