Full design automation of multi-state RNA devices to program gene expression using energy-based optimization.
Small RNAs (sRNAs) can operate as regulatory agents to control protein expression by interaction with the 5' untranslated region of the mRNA. We have developed a physicochemical framework, relying on base pair interaction energies, to design multi-state sRNA devices by solving an optimization p...
Guardado en:
Autores principales: | Guillermo Rodrigo, Thomas E Landrain, Eszter Majer, José-Antonio Daròs, Alfonso Jaramillo |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/36ff29ef71b04a09b075c750b2a94d3a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Concept and design of automated moving device for healthcare equipment
por: Faria N.M.S., et al.
Publicado: (2021) -
Optimized design for illusion device by genetic algorithm
por: Zhenzhong Yu, et al.
Publicado: (2021) -
Bayesian optimization with adaptive surrogate models for automated experimental design
por: Bowen Lei, et al.
Publicado: (2021) -
MULTI-PURPOSE OPTIMIZATION OF THE PRODUCT RELEASE PROGRAM
por: D. A. Alferev, et al.
Publicado: (2020) -
Optimal Planning Design of a District-Level Integrated Energy System Considering the Impacts of Multi-Dimensional Uncertainties: A Multi-Objective Interval Optimization Method
por: Hang Liu, et al.
Publicado: (2021)