Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs

Background: Data regarding antimicrobial pharmacokinetics (PK) in critically ill dogs are lacking and likely differ from those of healthy dogs. The aim of this work is to describe a population PK model for intravenous (IV) amoxicillin–clavulanic acid (AMC) in both healthy and sick dogs and to simula...

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Détails bibliographiques
Auteurs principaux: Maria D. Vegas Cómitre, Stefano Cortellini, Marc Cherlet, Mathias Devreese, Beatrice B. Roques, Alain Bousquet-Melou, Pierre-Louis Toutain, Ludovic Pelligand
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
MIC
ICU
Accès en ligne:https://doaj.org/article/3709d17f3feb47fe83bbefd066e8d366
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