Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation

Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation

Abstract Background Multiple sclerosis (MS) is a chronic autoimmune disease driven by sustained inflammation in the central nervous system. One of the pathological hallmarks of MS is extensive free radical production. However, the subsequent generation, potential pathological role, and detoxificatio...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jan Spaas, Wouter M. A. Franssen, Charly Keytsman, Laura Blancquaert, Tim Vanmierlo, Jeroen Bogie, Bieke Broux, Niels Hellings, Jack van Horssen, Dheeraj Kumar Posa, David Hoetker, Shahid P. Baba, Wim Derave, Bert O. Eijnde
Format: article
Langue:EN
Publié: BMC 2021
Sujets:
Acrolein
Carnosine
Multiple sclerosis
Neuroinflammation
Oxidative stress
Reactive carbonyl
Neurology. Diseases of the nervous system
RC346-429
Accès en ligne:https://doaj.org/article/3715f5de65d64b1e9a2469cd2e5cb244
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/3715f5de65d64b1e9a2469cd2e5cb244

Documents similaires