A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads

Characterizing the mechanical response of molecular motors involves the use of methods such as optical trapping to apply force. Here the authors develop a DNA origami nanospring to apply progressive force to human myosin VI, and discover that it adopts different stepping modes when subjected to low...

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Autores principales: M. Iwaki, S. F. Wickham, K. Ikezaki, T. Yanagida, W. M. Shih
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/37248553c4fb444db17e3f39d41d9635
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