A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads

Characterizing the mechanical response of molecular motors involves the use of methods such as optical trapping to apply force. Here the authors develop a DNA origami nanospring to apply progressive force to human myosin VI, and discover that it adopts different stepping modes when subjected to low...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	M. Iwaki, S. F. Wickham, K. Ikezaki, T. Yanagida, W. M. Shih
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/37248553c4fb444db17e3f39d41d9635
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:37248553c4fb444db17e3f39d41d9635
record_format	dspace
spelling	oai:doaj.org-article:37248553c4fb444db17e3f39d41d96352021-12-02T17:32:51ZA programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads10.1038/ncomms137152041-1723https://doaj.org/article/37248553c4fb444db17e3f39d41d96352016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13715https://doaj.org/toc/2041-1723Characterizing the mechanical response of molecular motors involves the use of methods such as optical trapping to apply force. Here the authors develop a DNA origami nanospring to apply progressive force to human myosin VI, and discover that it adopts different stepping modes when subjected to low load or high load.M. IwakiS. F. WickhamK. IkezakiT. YanagidaW. M. ShihNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q M. Iwaki S. F. Wickham K. Ikezaki T. Yanagida W. M. Shih A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads
description	Characterizing the mechanical response of molecular motors involves the use of methods such as optical trapping to apply force. Here the authors develop a DNA origami nanospring to apply progressive force to human myosin VI, and discover that it adopts different stepping modes when subjected to low load or high load.
format	article
author	M. Iwaki S. F. Wickham K. Ikezaki T. Yanagida W. M. Shih
author_facet	M. Iwaki S. F. Wickham K. Ikezaki T. Yanagida W. M. Shih
author_sort	M. Iwaki
title	A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads
title_short	A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads
title_full	A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads
title_fullStr	A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads
title_full_unstemmed	A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads
title_sort	programmable dna origami nanospring that reveals force-induced adjacent binding of myosin vi heads
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/37248553c4fb444db17e3f39d41d9635
work_keys_str_mv	AT miwaki aprogrammablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT sfwickham aprogrammablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT kikezaki aprogrammablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT tyanagida aprogrammablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT wmshih aprogrammablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT miwaki programmablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT sfwickham programmablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT kikezaki programmablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT tyanagida programmablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads AT wmshih programmablednaorigaminanospringthatrevealsforceinducedadjacentbindingofmyosinviheads
_version_	1718380177345478656

A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads

Ejemplares similares