Pairing a high-resolution statistical potential with a nucleobase-centric sampling algorithm for improving RNA model refinement

Predicting RNA structure from sequence is challenging due to the relative sparsity of experimentally-determined RNA 3D structures for model training. Here, the authors propose a way to incorporate knowledge on interactions at the atomic and base–base level to refine the prediction of RNA structures....

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Auteurs principaux: Peng Xiong, Ruibo Wu, Jian Zhan, Yaoqi Zhou
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
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Accès en ligne:https://doaj.org/article/3728b2ded75444fcbbd371504429c7bc
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