LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation

LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation

miR-205 is known to have context-dependent tumor suppressive or oncogenic roles. Here, the authors report the host gene of miR-205, MIR205HG as a nuclear lincRNA that maintains the basal identity of prostate cell and prevents luminal cell differentiation via the repression of interferon responsive g...

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Autores principales: Valentina Profumo, Barbara Forte, Stefano Percio, Federica Rotundo, Valentina Doldi, Elena Ferrari, Nicola Fenderico, Matteo Dugo, Dario Romagnoli, Matteo Benelli, Riccardo Valdagni, Diletta Dolfini, Nadia Zaffaroni, Paolo Gandellini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/3732cd911d6749edbdf73c6627e1003f
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https://doaj.org/article/3732cd911d6749edbdf73c6627e1003f

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