PARP2 mediates branched poly ADP-ribosylation in response to DNA damage

PARP1 and PARP2 of the PARP family enzymes are involved in DNA damage response. Here the authors report PARP2 activation mechanisms and its role in the formation of branched poly(ADP-ribose) chains in response to DNA damage.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Qian Chen, Muzaffer Ahmad Kassab, Françoise Dantzer, Xiaochun Yu
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/3782bba392cb4d86addb32c7ae61f0ac
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!