PARP2 mediates branched poly ADP-ribosylation in response to DNA damage

PARP1 and PARP2 of the PARP family enzymes are involved in DNA damage response. Here the authors report PARP2 activation mechanisms and its role in the formation of branched poly(ADP-ribose) chains in response to DNA damage.

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Autores principales:	Qian Chen, Muzaffer Ahmad Kassab, Françoise Dantzer, Xiaochun Yu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3782bba392cb4d86addb32c7ae61f0ac
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spelling	oai:doaj.org-article:3782bba392cb4d86addb32c7ae61f0ac2021-12-02T16:56:43ZPARP2 mediates branched poly ADP-ribosylation in response to DNA damage10.1038/s41467-018-05588-52041-1723https://doaj.org/article/3782bba392cb4d86addb32c7ae61f0ac2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05588-5https://doaj.org/toc/2041-1723PARP1 and PARP2 of the PARP family enzymes are involved in DNA damage response. Here the authors report PARP2 activation mechanisms and its role in the formation of branched poly(ADP-ribose) chains in response to DNA damage.Qian ChenMuzaffer Ahmad KassabFrançoise DantzerXiaochun YuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qian Chen Muzaffer Ahmad Kassab Françoise Dantzer Xiaochun Yu PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
description	PARP1 and PARP2 of the PARP family enzymes are involved in DNA damage response. Here the authors report PARP2 activation mechanisms and its role in the formation of branched poly(ADP-ribose) chains in response to DNA damage.
format	article
author	Qian Chen Muzaffer Ahmad Kassab Françoise Dantzer Xiaochun Yu
author_facet	Qian Chen Muzaffer Ahmad Kassab Françoise Dantzer Xiaochun Yu
author_sort	Qian Chen
title	PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
title_short	PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
title_full	PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
title_fullStr	PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
title_full_unstemmed	PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
title_sort	parp2 mediates branched poly adp-ribosylation in response to dna damage
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3782bba392cb4d86addb32c7ae61f0ac
work_keys_str_mv	AT qianchen parp2mediatesbranchedpolyadpribosylationinresponsetodnadamage AT muzafferahmadkassab parp2mediatesbranchedpolyadpribosylationinresponsetodnadamage AT francoisedantzer parp2mediatesbranchedpolyadpribosylationinresponsetodnadamage AT xiaochunyu parp2mediatesbranchedpolyadpribosylationinresponsetodnadamage
_version_	1718382733274644480

PARP2 mediates branched poly ADP-ribosylation in response to DNA damage

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