PARP2 mediates branched poly ADP-ribosylation in response to DNA damage

PARP1 and PARP2 of the PARP family enzymes are involved in DNA damage response. Here the authors report PARP2 activation mechanisms and its role in the formation of branched poly(ADP-ribose) chains in response to DNA damage.

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Autores principales: Qian Chen, Muzaffer Ahmad Kassab, Françoise Dantzer, Xiaochun Yu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Q
Acceso en línea:https://doaj.org/article/3782bba392cb4d86addb32c7ae61f0ac
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