Long-term immunogenicity and safety of a non-typeable Haemophilus influenzae-Moraxella catarrhalis vaccine: 4-year follow-up of a phase 1 multicentre trial

Long-term immunogenicity and safety of a non-typeable Haemophilus influenzae-Moraxella catarrhalis vaccine: 4-year follow-up of a phase 1 multicentre trial

A multicomponent vaccine has been developed to reduce the frequency of acute exacerbations of COPD associated with non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) infections, containing NTHi (PD and PE-PilA) and Mcat (UspA2) surface proteins. In a randomised, observer-bli...

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Autores principales: Philippe De Smedt, Geert Leroux-Roels, Corinne Vandermeulen, Annaelisa Tasciotti, Gennaro Di Maro, Marie Dozot, Daniela Casula, Margherita Annaratone, Daniele Riccucci, Ashwani Kumar Arora
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Acute exacerbation
Antibody persistence
Clinical trial
COPD
Haemophilus influenzae
Moraxella catarrhalis
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/378e0635c1c34397a8de8fc1124c2db9
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https://doaj.org/article/378e0635c1c34397a8de8fc1124c2db9

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