Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation

Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation

Background: Respiratory syncytial virus (RSV) can cause varying degrees of lung inflammation in children. Qingfei Oral Liquid (QF) is effective in treating childhood RSV-induced lung inflammation (RSV-LI) in clinics, but its pharmacological profiles and mechanisms remain unclear.Methods: This study...

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Bibliographic Details
Main Authors: Lili Lin, Li An, Hui Chen, Lu Feng, Mengjiang Lu, Yuling Liu, Chu Chu, Jinjun Shan, Tong Xie, Xiaorong Wang, Shouchuan Wang
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
respiratory syncytial virus
qingfei oral liquid
network pharmacology
lipidomics
excessive autophagy
PI3K/AKT/mTOR
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/37b2cc25bc94426a98bbd5a5377ce12c
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https://doaj.org/article/37b2cc25bc94426a98bbd5a5377ce12c

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