Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor

Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor

Arf GTPase-Activating proteins (ArfGAPs) mediate the hydrolysis of GTP bound to ADP-ribosylation factors (Arfs), which are critical to form transport intermediates. ArfGAPs have been thought to be negative regulators of Arfs; however, accumulating evidence indicates that ArfGAPs are important for ca...

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Autores principales: Asano Watanabe, Hikari Hataida, Naoya Inoue, Kosuke Kamon, Keigo Baba, Kuniaki Sasaki, Rika Kimura, Honoka Sasaki, Yuka Eura, Wei-Fen Ni, Yuji Shibasaki, Satoshi Waguri, Koichi Kokame, Yoko Shiba
Formato: article
Lenguaje:EN
Publicado: The Company of Biologists 2021
Materias:
arf
arfgap
secretory granule
exocytosis
vwf
wpb
Science
Q
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/37c4573f900a4b4b9c4c349226fa51b5
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https://doaj.org/article/37c4573f900a4b4b9c4c349226fa51b5

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