SPARC coordinates extracellular matrix remodeling and efficient recruitment to and migration of antigen-specific T cells in the brain following infection

Abstract Central nervous system (CNS) injury and infection can result in profound tissue remodeling in the brain, the mechanism and purpose of which is poorly understood. Infection with the protozoan parasite Toxoplasma gondii causes chronic infection and inflammation in the brain parenchyma. Contro...

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Autores principales: Kathryn E. McGovern, J. Philip Nance, Clément N. David, Reed E. S. Harrison, Shahani Noor, Danielle Worth, Tyler A. Landrith, Andre Obenaus, Monica J. Carson, Dimitrios Morikis, Emma H. Wilson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/37ea326e19414df5ac396cbe47c69847
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