Immunogenicity and protective efficacy of prime-boost immunization in mice vaccinated with live and inactivated influenza A (H5N1) vaccines

Avian influenza A (H1N1) in humans is characterized by severe clinical manifestation and high mortality. The main drawback of current human H5N1 vaccines is related to low immunogenicity. Prime-boost vaccination is considered as an effective approach to enhance vaccine immunogenicity. The aim of thi...

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Auteurs principaux: I. Losev, G. Petukhova, I. Isakova-Sivak, L. Rudenko
Format: article
Langue:RU
Publié: Sankt-Peterburg : NIIÈM imeni Pastera 2019
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Accès en ligne:https://doaj.org/article/37f3fc5a738741eea67975ee79e4b01b
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