Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis.
Vascular abnormalities contribute to many diseases such as cancer and diabetic retinopathy. In angiogenesis new blood vessels, headed by a migrating tip cell, sprout from pre-existing vessels in response to signals, e.g., vascular endothelial growth factor (VEGF). Tip cells meet and fuse (anastomosi...
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Main Authors: | Katie Bentley, Giovanni Mariggi, Holger Gerhardt, Paul A Bates |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2009
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Online Access: | https://doaj.org/article/37fb55b7fb9c437a91a2d39d5ef78b8d |
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