Structural and Biochemical Characterization of Poly-ADP-ribose Polymerase from Trypanosoma brucei

Abstract Trypanosoma brucei is a unicellular parasite responsible for African trypanosomiasis or sleeping sickness. It contains a single PARP enzyme opposed to many higher eukaryotes, which have numerous PARPs. PARPs are responsible for a post-translational modification, ADP-ribosylation, regulating...

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Bibliographic Details
Main Authors: Teemu Haikarainen, Mariana Schlesinger, Ezeogo Obaji, Silvia H. Fernández Villamil, Lari Lehtiö
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/383567bfb60a4e1f9f36829cf9b4a8ca
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