Identification of Nedd4 E3 ubiquitin ligase as a binding partner and regulator of MAK-V protein kinase.
MAK-V/Hunk is a scantily characterized AMPK-like protein kinase. Recent findings identified MAK-V as a pro-survival and anti-apoptotic protein and revealed its role in embryonic development as well as in tumorigenesis and metastasis. However molecular mechanisms of MAK-V action and regulation of its...
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Auteurs principaux: | , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/384c65e2d6b54befaad2724241647885 |
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