Genetic and molecular analyses of PEG10 reveal new aspects of genomic organization, transcription and translation.

The paternally expressed gene PEG10 is a retrotransposon derived gene adapted through mammalian evolution located on human chromosome 7q21. PEG10 codes for at least two proteins, PEG10-RF1 and PEG10-RF1/2, by -1 frameshift translation. Overexpression or reinduced PEG10 expression was seen in maligna...

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Bibliographic Details
Main Authors: Heike Lux, Heiko Flammann, Mathias Hafner, Andreas Lux
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
R
Q
Online Access:https://doaj.org/article/3863372bcb0743a085521b7d5eb9d63d
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