Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance

ABSTRACT Neisseria gonorrhoeae is an obligate human pathogen and causative agent of the sexually transmitted infection (STI) gonorrhea. The most predominant and clinically important multidrug efflux system in N. gonorrhoeae is the multiple transferrable resistance (Mtr) pump, which mediates resistan...

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Autores principales: Meinan Lyu, Mitchell A. Moseng, Jennifer L. Reimche, Concerta L. Holley, Vijaya Dhulipala, Chih-Chia Su, William M. Shafer, Edward W. Yu
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/38956fe7f1b843b0a44c5ce5d08045e4
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