Coupling of Polo kinase activation to nuclear localization by a bifunctional NLS is required during mitotic entry

Drosophila Polo kinase is the founding member of the Polo-Like Kinase (PLK) family and a master regulator of mitosis and cytokinesis. Here the authors uncover a molecular mechanism for the spatiotemporal regulation of Polo kinase during mitotic entry through a phosphorylation event that triggers nuc...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: David Kachaner, Damien Garrido, Haytham Mehsen, Karine Normandin, Hugo Lavoie, Vincent Archambault
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/389f2a1bbd0141f2bc14a48f419d8a3f
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!