P-body proteins regulate transcriptional rewiring to promote DNA replication stress resistance
P-bodies form in response to stress and act as sites of mRNA storage and degradation. Here the authors identify the mRNA targets of P-bodies during DNA replication stress, and show that P-body proteins act to prevent toxic accumulation of these target transcripts.
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Main Authors: | Raphael Loll-Krippleber, Grant W. Brown |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/38b91d8a311c4ba5b0dd936cdd11a4b6 |
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