Recombinant human plasma phospholipid transfer protein (PLTP) to prevent bacterial growth and to treat sepsis

Recombinant human plasma phospholipid transfer protein (PLTP) to prevent bacterial growth and to treat sepsis

Abstract Although plasma phospholipid transfer protein (PLTP) has been mainly studied in the context of atherosclerosis, it shares homology with proteins involved in innate immunity. Here, we produced active recombinant human PLTP (rhPLTP) in the milk of new lines of transgenic rabbits. We successfu...

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Main Authors: Valérie Deckert, Stéphanie Lemaire, Pierre-Jean Ripoll, Jean-Paul Pais de Barros, Jérôme Labbé, Caroline Chabert-Le Borgne, Véronique Turquois, Guillaume Maquart, Delphine Larose, Nicolas Desroche, Franck Ménétrier, Naig Le Guern, Lorène J. Lebrun, Catherine Desrumaux, Thomas Gautier, Jacques Grober, Charles Thomas, David Masson, Louis-Marie Houdebine, Laurent Lagrost
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/38bc086aee0d4b64bfb9adb2801c05a8
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