Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance

Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance

ABSTRACT Flaviviruses are controlled by adaptive immune responses but are exquisitely sensitive to interferon-stimulated genes (ISGs). How coinfections, particularly simian immunodeficiency viruses (SIVs), that induce robust ISG signatures influence flavivirus clearance and pathogenesis is unclear....

Full description

Saved in:
Bibliographic Details
Main Authors: Carol L. Vinton, Samuel J. Magaziner, Kimberly A. Dowd, Shelly J. Robertson, Emerito Amaro-Carambot, Erik P. Karmele, Alexandra M. Ortiz, Carly E. Starke, Joseph C. Mudd, Stephen S. Whitehead, Sonja M. Best, Theodore C. Pierson, Heather D. Hickman, Jason M. Brenchley
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
SIV
ZIKV
innate immunity
type I interferon
Microbiology
QR1-502
Online Access:https://doaj.org/article/38d4fedb46b448498b0af972c8906ef0
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/38d4fedb46b448498b0af972c8906ef0

Similar Items