Change in Cofactor Specificity of Oxidoreductases by Adaptive Evolution of an <named-content content-type="genus-species">Escherichia coli</named-content> NADPH-Auxotrophic Strain
ABSTRACT The nicotinamide cofactor specificity of enzymes plays a key role in regulating metabolic processes and attaining cellular homeostasis. Multiple studies have used enzyme engineering tools or a directed evolution approach to switch the cofactor preference of specific oxidoreductases. However...
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| Auteurs principaux: | , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2021
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| Accès en ligne: | https://doaj.org/article/38fd0ac8befb44b2b7318eb60777cb4e |
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