An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage

An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage

Mechanisms underlying the cardiotoxicity associated with thoracic irradiation and doxorubicin treatment during anticancer therapy remain poorly understood. Here the authors show that treatment with an antibody against the L1 cell adhesion molecule inhibits nuclear L1CAM translocation, thereby contro...

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Autores principales: Jae-Kyung Nam, A-Ram Kim, Seo-Hyun Choi, Ji-Hee Kim, Kyu Jin Choi, Seulki Cho, Jae Won Lee, Hyun-Jai Cho, Yoo-Wook Kwon, Jaeho Cho, Kwang Seok Kim, Joon Kim, Hae-June Lee, Tae Sup Lee, Sangwoo Bae, Hyo Jeong Hong, Yoon-Jin Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/390ba1c3b7ef40a4a2315adde73d9f10
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https://doaj.org/article/390ba1c3b7ef40a4a2315adde73d9f10

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