Engineering human pluripotent stem cells into a functional skeletal muscle tissue

The generation of functional skeletal muscle tissue from human pluripotent stem cells has not been reported. Here, the authors describe engineering of contractile skeletal muscle bundles in culture, which become vascularized and maintain functionality when transplanted into mice.

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Autores principales: Lingjun Rao, Ying Qian, Alastair Khodabukus, Thomas Ribar, Nenad Bursac
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/39c072b874824259bdaae64f626b75e9
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