Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.

Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.

Melanoma is the most aggressive form of skin cancer, with fast progression and early dissemination mediated by the melanoma inhibitory activity (MIA) protein. Here, we discovered that dimerization of MIA is required for functional activity through mutagenesis of MIA which showed the correlation betw...

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Autores principales: Jennifer Schmidt, Alexander Riechers, Raphael Stoll, Thomas Amann, Florian Fink, Thilo Spruss, Wolfram Gronwald, Burkhard König, Claus Hellerbrand, Anja Katrin Bosserhoff
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/39e4ad3f93ac47aba5e3380637e30990
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https://doaj.org/article/39e4ad3f93ac47aba5e3380637e30990

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