N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
Many fungi are able to metabolise environmental N-acetylglucosamine, however the mechanism by which this molecule is sensed is unclear. Su and Lu et al. show that Candida albicansNGS1 fulfils this function by mediating N-acetylglucosamine-dependent histone acetylation at target genes.
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2016
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| Accès en ligne: | https://doaj.org/article/39f0b622e1ec47a6aa3d390cdd3c6262 |
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