N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi

Many fungi are able to metabolise environmental N-acetylglucosamine, however the mechanism by which this molecule is sensed is unclear. Su and Lu et al. show that Candida albicansNGS1 fulfils this function by mediating N-acetylglucosamine-dependent histone acetylation at target genes.

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Autores principales: Chang Su, Yang Lu, Haoping Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/39f0b622e1ec47a6aa3d390cdd3c6262
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