N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi

Many fungi are able to metabolise environmental N-acetylglucosamine, however the mechanism by which this molecule is sensed is unclear. Su and Lu et al. show that Candida albicansNGS1 fulfils this function by mediating N-acetylglucosamine-dependent histone acetylation at target genes.

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Detalles Bibliográficos
Autores principales:	Chang Su, Yang Lu, Haoping Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/39f0b622e1ec47a6aa3d390cdd3c6262
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spelling	oai:doaj.org-article:39f0b622e1ec47a6aa3d390cdd3c62622021-12-02T17:31:50ZN-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi10.1038/ncomms129162041-1723https://doaj.org/article/39f0b622e1ec47a6aa3d390cdd3c62622016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms12916https://doaj.org/toc/2041-1723Many fungi are able to metabolise environmental N-acetylglucosamine, however the mechanism by which this molecule is sensed is unclear. Su and Lu et al. show that Candida albicansNGS1 fulfils this function by mediating N-acetylglucosamine-dependent histone acetylation at target genes.Chang SuYang LuHaoping LiuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chang Su Yang Lu Haoping Liu N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
description	Many fungi are able to metabolise environmental N-acetylglucosamine, however the mechanism by which this molecule is sensed is unclear. Su and Lu et al. show that Candida albicansNGS1 fulfils this function by mediating N-acetylglucosamine-dependent histone acetylation at target genes.
format	article
author	Chang Su Yang Lu Haoping Liu
author_facet	Chang Su Yang Lu Haoping Liu
author_sort	Chang Su
title	N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
title_short	N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
title_full	N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
title_fullStr	N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
title_full_unstemmed	N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi
title_sort	n-acetylglucosamine sensing by a gcn5-related n-acetyltransferase induces transcription via chromatin histone acetylation in fungi
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/39f0b622e1ec47a6aa3d390cdd3c6262
work_keys_str_mv	AT changsu nacetylglucosaminesensingbyagcn5relatednacetyltransferaseinducestranscriptionviachromatinhistoneacetylationinfungi AT yanglu nacetylglucosaminesensingbyagcn5relatednacetyltransferaseinducestranscriptionviachromatinhistoneacetylationinfungi AT haopingliu nacetylglucosaminesensingbyagcn5relatednacetyltransferaseinducestranscriptionviachromatinhistoneacetylationinfungi
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N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi

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