DNA binding properties of the small cascade subunit Csa5.
CRISPR-Cas systems provide immunity against viral attacks in archaeal and bacterial cells. Type I systems employ a Cas protein complex termed Cascade, which utilizes small CRISPR RNAs to detect and degrade the exogenic DNA. A small sequence motif, the PAM, marks the foreign substrates. Previously, a...
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Main Authors: | Michael Daume, André Plagens, Lennart Randau |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/3a03f9be8a554109a41c8727a27fc7e6 |
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