Polyomavirus T Antigen Induces <italic toggle="yes">APOBEC3B</italic> Expression Using an LXCXE-Dependent and TP53-Independent Mechanism
ABSTRACT APOBEC3B is a single-stranded DNA cytosine deaminase with beneficial innate antiviral functions. However, misregulated APOBEC3B can also be detrimental by inflicting APOBEC signature C-to-T and C-to-G mutations in genomic DNA of multiple cancer types. Polyomavirus and papillomavirus oncopro...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/3a082cd74ff645c9aabca1b686b2927e |
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