Calcineurin Aα Contributes to IgE-Dependent Mast-Cell Mediator Secretion in Allergic Inflammation

Mast cells (MCs) are key mediators of allergic inflammation through the activation of cross-linked immunoglobulin E (IgE) bound to the high-affinity IgE receptor (FcϵRI) on the cell surface, leading to the release of biologically potent mediators, either from preformed granules or newly synthesized....

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Autores principales: Edwin Leong, Zheng Pang, Andrew W. Stadnyk, Tong-Jun Lin
Formato: article
Lenguaje:EN
Publicado: Karger Publishers 2021
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Acceso en línea:https://doaj.org/article/3a24870f55f54c1884bbd465257c0501
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