Calcineurin Aα Contributes to IgE-Dependent Mast-Cell Mediator Secretion in Allergic Inflammation
Mast cells (MCs) are key mediators of allergic inflammation through the activation of cross-linked immunoglobulin E (IgE) bound to the high-affinity IgE receptor (FcϵRI) on the cell surface, leading to the release of biologically potent mediators, either from preformed granules or newly synthesized....
Guardado en:
Autores principales: | Edwin Leong, Zheng Pang, Andrew W. Stadnyk, Tong-Jun Lin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Karger Publishers
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/3a24870f55f54c1884bbd465257c0501 |
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