Biophysical properties of a tau seed

Abstract Pathogenesis of tauopathies involves conversion of tau monomer into pathological tau conformers that serve as templates to recruit native tau into growing assemblies. Small soluble tau seeds have been proposed to drive pathological tau assembly in vitro, in cells and in vivo. We have previo...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhiqiang Hou, Dailu Chen, Bryan D. Ryder, Lukasz A. Joachimiak
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/3a52c751ad3f486f923d73a2de32d49c
Tags: Add Tag
No Tags, Be the first to tag this record!