Molecular Insights into Function and Competitive Inhibition of <italic toggle="yes">Pseudomonas aeruginosa</italic> Multiple Virulence Factor Regulator

Molecular Insights into Function and Competitive Inhibition of <italic toggle="yes">Pseudomonas aeruginosa</italic> Multiple Virulence Factor Regulator

ABSTRACT New approaches to antimicrobial drug discovery are urgently needed to combat intractable infections caused by multidrug-resistant (MDR) bacteria. Multiple virulence factor regulator (MvfR or PqsR), a Pseudomonas aeruginosa quorum sensing transcription factor, regulates functions important i...

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Autores principales: Tomoe Kitao, Francois Lepine, Seda Babloudi, Frederick Walte, Stefan Steinbacher, Klaus Maskos, Michael Blaesse, Michele Negri, Michael Pucci, Bob Zahler, Antonio Felici, Laurence G. Rahme
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
MvfR
PqsR
Pseudomonas aeruginosa
structural analysis
X-ray crystallography
antivirulence
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/3a5377cb41f442beb617a5562a681113
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https://doaj.org/article/3a5377cb41f442beb617a5562a681113

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