An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells
Intravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that produce an artificial T-cell receptor for use in immunotherapy. Chimeric antige...
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| Auteurs principaux: | , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Urology Research Center
2020
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| Accès en ligne: | https://doaj.org/article/3a53ef52572b4e01b9c5a4e99fb990af |
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| Résumé: | Intravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that produce an artificial T-cell receptor for use in immunotherapy. Chimeric antigen receptors are receptor proteins that have been engineered to give T cells the new ability to target a specific protein Its effect is mostly achieved using activating the immune system; the same mechanism proposed likely for chimeric antigen receptor (CAR) T cells. Hence CAR-T cell therapy could be considered for bladder cancer treatment. |
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