Diagnostic value of skin RT-QuIC in Parkinson’s disease: a two-laboratory study

Abstract Skin α-synuclein deposition is considered a potential biomarker for Parkinson’s disease (PD). Real-time quaking-induced conversion (RT-QuIC) is a novel, ultrasensitive, and efficient seeding assay that enables the detection of minute amounts of α-synuclein aggregates. We aimed to determine...

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Autores principales: Anastasia Kuzkina, Connor Bargar, Daniela Schmitt, Jonas Rößle, Wen Wang, Anna-Lena Schubert, Curtis Tatsuoka, Steven A. Gunzler, Wen-Quan Zou, Jens Volkmann, Claudia Sommer, Kathrin Doppler, Shu G. Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3a90bad7b05e46a19ec4caa217356998
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