2,2'-diphenyl-3,3'-diindolylmethane: a potent compound induces apoptosis in breast cancer cells by inhibiting EGFR pathway.

2,2'-diphenyl-3,3'-diindolylmethane: a potent compound induces apoptosis in breast cancer cells by inhibiting EGFR pathway.

Despite recent advances in medicine, 30-40% of patients with breast cancer show recurrence underscoring the need for improved effective therapy. In this study, by in vitro screening we have selected a novel synthetic indole derivative 2,2'-diphenyl-3,3'-diindolylmethane (DPDIM) as a potent...

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Auteurs principaux: Arijit Bhowmik, Nilanjana Das, Uttam Pal, Madhumita Mandal, Seemana Bhattacharya, Moumita Sarkar, Parasuraman Jaisankar, Nakul C Maiti, Mrinal K Ghosh
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/3aa39d79e65245f7bfda713766dd5396
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https://doaj.org/article/3aa39d79e65245f7bfda713766dd5396

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