Small-molecule quinolinol inhibitor identified provides protection against BoNT/A in mice.

Botulinum neurotoxins (BoNTs), etiological agents of the life threatening neuroparalytic disease botulism, are the most toxic substances currently known. The potential for the use as bioweapon makes the development of small-molecule inhibitor against these deadly toxins is a top priority. Currently,...

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Auteurs principaux: Padma Singh, Manglesh Kumar Singh, Dilip Chaudhary, Vinita Chauhan, Pranay Bharadwaj, Apurva Pandey, Nisha Upadhyay, Ram Kumar Dhaked
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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R
Q
Accès en ligne:https://doaj.org/article/3aa7304962a043a48e0294dc4c1e006e
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