Genetic engineering of porcine endothelial cell lines for evaluation of human-to-pig xenoreactive immune responses

Abstract Xenotransplantation (cross-species transplantation) using genetically-engineered pig organs offers a potential solution to address persistent organ shortage. Current evaluation of porcine genetic modifications is to monitor the nonhuman primate immune response and survival after pig organ x...

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Main Authors: Ping Li, Julia R. Walsh, Kevin Lopez, Abdulkadir Isidan, Wenjun Zhang, Angela M. Chen, William C. Goggins, Nancy G. Higgins, Jianyun Liu, Randy R. Brutkiewicz, Lester J. Smith, Hidetaka Hara, David K. C. Cooper, Burcin Ekser
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/3ae22fee438c45fa9103891970992214
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