Calcium-activated chloride channels clamp odor-evoked spike activity in olfactory receptor neurons

Abstract The calcium-activated chloride channel anoctamin-2 (Ano2) is thought to amplify transduction currents in olfactory receptor neurons (ORNs), a hypothesis supported by previous studies in dissociated neurons from Ano2 −/− mice. Paradoxically, despite a reduction in transduction currents in An...

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Bibliographic Details
Main Authors: Joseph D. Zak, Julien Grimaud, Rong-Chang Li, Chih-Chun Lin, Venkatesh N. Murthy
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/3aec2c696f2b468d9d6f10a8e92a9143
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