The transcription factor NFAT5 is required for cyclin expression and cell cycle progression in cells exposed to hypertonic stress.

The transcription factor NFAT5 is required for cyclin expression and cell cycle progression in cells exposed to hypertonic stress.

<h4>Background</h4>Hypertonicity can perturb cellular functions, induce DNA damage-like responses and inhibit proliferation. The transcription factor NFAT5 induces osmoprotective gene products that allow cells to adapt to sustained hypertonic conditions. Although it is known that NFAT5-d...

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Autores principales: Katherine Drews-Elger, M Carmen Ortells, Anjana Rao, Cristina López-Rodriguez, Jose Aramburu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/3b08b906199040358b5efac7ba4ed48a
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