The transcription factor NFAT5 is required for cyclin expression and cell cycle progression in cells exposed to hypertonic stress.
<h4>Background</h4>Hypertonicity can perturb cellular functions, induce DNA damage-like responses and inhibit proliferation. The transcription factor NFAT5 induces osmoprotective gene products that allow cells to adapt to sustained hypertonic conditions. Although it is known that NFAT5-d...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
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Public Library of Science (PLoS)
2009
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| Accès en ligne: | https://doaj.org/article/3b08b906199040358b5efac7ba4ed48a |
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