Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent

Selective C-H trifluoromethoxylation of pyridines remains a formidable synthetic challenge. Here, the authors report a silver-mediated late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagents with trifluoromethoxide anion.

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Bibliographic Details
Main Authors: Zhijie Deng, Mingxin Zhao, Feng Wang, Pingping Tang
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Q
Online Access:https://doaj.org/article/3b24d1bb6e474a11b42f442f91801512
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