Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent
Selective C-H trifluoromethoxylation of pyridines remains a formidable synthetic challenge. Here, the authors report a silver-mediated late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagents with trifluoromethoxide anion.
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Nature Portfolio
2020
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oai:doaj.org-article:3b24d1bb6e474a11b42f442f918015122021-12-02T16:51:35ZSelective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent10.1038/s41467-020-16451-x2041-1723https://doaj.org/article/3b24d1bb6e474a11b42f442f918015122020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16451-xhttps://doaj.org/toc/2041-1723Selective C-H trifluoromethoxylation of pyridines remains a formidable synthetic challenge. Here, the authors report a silver-mediated late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagents with trifluoromethoxide anion.Zhijie DengMingxin ZhaoFeng WangPingping TangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q Zhijie Deng Mingxin Zhao Feng Wang Pingping Tang Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent |
description |
Selective C-H trifluoromethoxylation of pyridines remains a formidable synthetic challenge. Here, the authors report a silver-mediated late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagents with trifluoromethoxide anion. |
format |
article |
author |
Zhijie Deng Mingxin Zhao Feng Wang Pingping Tang |
author_facet |
Zhijie Deng Mingxin Zhao Feng Wang Pingping Tang |
author_sort |
Zhijie Deng |
title |
Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent |
title_short |
Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent |
title_full |
Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent |
title_fullStr |
Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent |
title_full_unstemmed |
Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent |
title_sort |
selective c-h trifluoromethoxylation of (hetero)arenes as limiting reagent |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/3b24d1bb6e474a11b42f442f91801512 |
work_keys_str_mv |
AT zhijiedeng selectivechtrifluoromethoxylationofheteroarenesaslimitingreagent AT mingxinzhao selectivechtrifluoromethoxylationofheteroarenesaslimitingreagent AT fengwang selectivechtrifluoromethoxylationofheteroarenesaslimitingreagent AT pingpingtang selectivechtrifluoromethoxylationofheteroarenesaslimitingreagent |
_version_ |
1718382910855184384 |