Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent

Selective C-H trifluoromethoxylation of pyridines remains a formidable synthetic challenge. Here, the authors report a silver-mediated late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagents with trifluoromethoxide anion.

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Autores principales: Zhijie Deng, Mingxin Zhao, Feng Wang, Pingping Tang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/3b24d1bb6e474a11b42f442f91801512
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spelling oai:doaj.org-article:3b24d1bb6e474a11b42f442f918015122021-12-02T16:51:35ZSelective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent10.1038/s41467-020-16451-x2041-1723https://doaj.org/article/3b24d1bb6e474a11b42f442f918015122020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16451-xhttps://doaj.org/toc/2041-1723Selective C-H trifluoromethoxylation of pyridines remains a formidable synthetic challenge. Here, the authors report a silver-mediated late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagents with trifluoromethoxide anion.Zhijie DengMingxin ZhaoFeng WangPingping TangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhijie Deng
Mingxin Zhao
Feng Wang
Pingping Tang
Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent
description Selective C-H trifluoromethoxylation of pyridines remains a formidable synthetic challenge. Here, the authors report a silver-mediated late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagents with trifluoromethoxide anion.
format article
author Zhijie Deng
Mingxin Zhao
Feng Wang
Pingping Tang
author_facet Zhijie Deng
Mingxin Zhao
Feng Wang
Pingping Tang
author_sort Zhijie Deng
title Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent
title_short Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent
title_full Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent
title_fullStr Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent
title_full_unstemmed Selective C-H trifluoromethoxylation of (hetero)arenes as limiting reagent
title_sort selective c-h trifluoromethoxylation of (hetero)arenes as limiting reagent
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/3b24d1bb6e474a11b42f442f91801512
work_keys_str_mv AT zhijiedeng selectivechtrifluoromethoxylationofheteroarenesaslimitingreagent
AT mingxinzhao selectivechtrifluoromethoxylationofheteroarenesaslimitingreagent
AT fengwang selectivechtrifluoromethoxylationofheteroarenesaslimitingreagent
AT pingpingtang selectivechtrifluoromethoxylationofheteroarenesaslimitingreagent
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