Discovering subgroups of patients from DNA copy number data using NMF on compacted matrices.

In the study of complex genetic diseases, the identification of subgroups of patients sharing similar genetic characteristics represents a challenging task, for example, to improve treatment decision. One type of genetic lesion, frequently investigated in such disorders, is the change of the DNA cop...

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Autores principales: Cassio P de Campos, Paola M V Rancoita, Ivo Kwee, Emanuele Zucca, Marco Zaffalon, Francesco Bertoni
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/3b3b6f275b3c4c6bbcf1e0907df737e6
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